Intestinal fibrogenesis in inflammatory intestinal disorders
نویسندگان
چکیده
The article deals with chronic inflammatory processes of the intestines and their complications that contribute to gradual accumulation deep transmural lesions intestinal wall, including narrowings, development obstruction, abscesses, fistulas. Both bowel diseases lead onset diarrhea, abdominal pain, anemia caused by pathology. Detecting disease activity severity is crucial importance in treatment intensity at early later stages illness when monitoring measures effectiveness. main molecular mediators fibrogenesis are studied article, results fibrosis visualization technologies summarized, possibilities for expanding quantitative magnetic resonance imaging, computed tomography, ultrasound encouraging potential non-invasive elastography methods discussed.
منابع مشابه
The Role of Intestinal Microbiota in Cognitive Disorders
Cognitive disorders are one of the major public health issues in older population worldwide. Problems in forming and storing new memories, short-term memory impairment, and other cognitive problems are common symptoms of cognitive disorders that have no definite treatment yet. Recent studies have shown an association between gut microbiota and cognitive impairments described as microbiota-gut-...
متن کاملIntestinal inflammatory myofibroblastic tumour.
BACKGROUND Inflammatory myofibroblastic tumours (IMFTs) are rare tumours characterised by nosologic, histogenetic and aetiopathogenetic controversy and variable clinicopathological features. We report our experience with intestinal-IMFTs (I-IMFTs) that have been reported mainly as single case reports to date. METHODS Five patients with I-IMFTs, identified between 2005 and 2008, formed the stu...
متن کاملContribution of Intestinal Smooth Muscle to Crohn’s Disease Fibrogenesis
Mesenchymal cells transdifferentiation and extracellular matrix deposition are involved in the fibrotic process of Crohn's disease (CD). Mesenchymal smooth muscle cells (SMCs) de-differentiation, driven by Platelet-derived growth factor (PDGF) that counteracts Transforming growth factor (TGF-β) has been studied in vascular muscle. The role of SMCs in intestinal fibrogenesis is still not clearly...
متن کاملAutism and Schizophrenia: Intestinal Disorders.
We examined Dohan's hypothesis that schizophrenia is associated with the absorption of "exorphins" contained in gluten and casein. In addition, because of the work of Reichelt et al. (Reichelt, K.L., Saelid, G., Lindback, J. and Orbeck, H. (1986) Biological Psychiatry 21:1279-1290) and Rodriguez et al. (Rodriguez, Trav, A.L., Barreiro Marin, R, Galvez, Borrero, I.M., del Olmo Romero-Nieva, F. a...
متن کاملIntestinal Epithelium in Inflammatory Bowel Disease
The intestinal epithelium has a strategic position as a protective physical barrier to luminal microbiota and actively contributes to the mucosal immune system. This barrier is mainly formed by a monolayer of specialized intestinal epithelial cells (IECs) that are crucial in maintaining intestinal homeostasis. Therefore, dysregulation within the epithelial layer can increase intestinal permeabi...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: ?????????????????
سال: 2023
ISSN: ['2384-101X', '2672-1163']
DOI: https://doi.org/10.22141/2308-2097.56.4.2022.518